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Lymphedema is least likely caused by which of the following?
Liver disease
Heart failure
Venous insufficiency
Infection
The correct answer is: Liver disease
Lymphedema is primarily associated with issues related to the lymphatic system, where there is an accumulation of lymph fluid in tissues, often due to obstruction or damage to the lymphatic vessels. The correct answer points to liver disease as the least likely cause because liver conditions primarily affect the liver function and may lead to issues like ascites (fluid accumulation in the abdominal cavity) but do not directly impair the lymphatic system's ability to drain fluid from the tissues. Heart failure can contribute to lymphedema by causing fluid overload in the body, which may lead to increased lymphatic workload and potential overflow. Venous insufficiency also results in fluid buildup, as the veins struggle to return blood to the heart, which can put additional pressure on the lymphatic system and contribute to lymphedema. Infections, such as cellulitis, can lead to localized swelling, which again can impede lymphatic drainage. Therefore, while liver disease can cause fluid retention, it does not typically affect lymphatic circulation directly, making it the least likely cause of lymphedema among the options provided.